PGT-A（胚胎染色体非整倍体检测）是指在体外受精获得的胚胎移植前，对其染色体进行检测的过程。

PGT-A refers to the genetic testing performed on embryos obtained through IVF to check for chromosomal abnormalities before implantation.

在胚胎发育至囊胚阶段后，对滋养外胚层的一部分进行活检，取出少量细胞并提交至检测机构进行染色体数目检测。

After fertilization, embryos are cultured until the blastocyst stage, where a small sample of the trophectoderm is biopsied, and several cells are extracted for analysis. These cells are submitted to a testing facility to evaluate chromosomal numbers.

• •当胚胎的状态不佳（例如，滋养外胚层细胞稀少）时，采集的细胞数量可能不足以进行检测。此外，采集到的细胞状态可能导致无法进行检测或无法得到检测结果。在这种情况下，仍需支付费用。未进行检测的胚胎不意味着其存在异常，移植是可能的。如果您希望不进行未检测胚胎的冷冻保存（即废弃），请提前告知我们。
• •关于性染色体（性别），除非存在数量异常，否则我们无法告知。
• •检测结果显示异常的胚胎，如果患者希望，仍可以进行移植及冷冻保存或延长保存期限。（如果保存期限到期而未进行续期手续，将予以废弃。）
• •即使检测结果正常，也不能保证100%避免怀孕或流产。与一般怀孕一样，即使没有异常，仍然可能发生原因不明的流产。
• •本次检测是采集胚胎的滋养外胚层（将形成胎盘的细胞）进行检测，因此无法100%检测内细胞团（将形成胎儿的细胞）。已报告的检测精度为99.4%。
• •如果希望进行本次检测，需在取卵前向医生申请。请提交申请表。

• •If the blastocyst condition is not optimal (e.g., insufficient trophectoderm cells), there may not be enough cells for analysis, and testing may not be possible. Additionally, the state of the extracted cells can affect the ability to test or yield results. Fees will still apply in such cases. Not being able to test does not imply the blastocyst is abnormal, and transfer may still be feasible. If you prefer not to cryopreserve (discard) blastocysts that cannot be tested, please inform us in advance.
• •Information regarding sex chromosomes (gender) cannot be disclosed except in cases of numerical abnormalities.
• •If testing reveals abnormalities, embryo transfer and cryopreservation can proceed at the patient’s request (please note that if the preservation period expires without renewal procedures, disposal will occur).
• •Even with normal test results, we cannot guarantee 100% avoidance of pregnancy loss, as unexplained miscarriages may still occur even in normal pregnancies.
• •This test samples the trophectoderm (cells that will form the placenta), meaning 100% testing of the inner cell mass (cells that will become the fetus) is not possible. The accuracy is reported to be 99.4%.
• •If you wish to undergo this testing, you must apply to your physician prior to egg retrieval, and we ask for the submission of an application form.

• •成功移植正常胚胎后，妊娠率将提高。
• •成功移植正常胚胎后，流产率将降低。

• •可能需要较长时间才能获得正常胚胎进行移植。
• •当前可实施的患者有限。
• •对于马赛克胚胎，结果的判断可能较为困难。

• •Higher pregnancy rates when transferring normal embryos.
• •Lower miscarriage rates when transferring normal embryos.

• •Obtaining normal embryos may take longer, delaying transfer.
• •Currently, the procedure is limited to specific candidates.
• •Results may indicate mosaic embryos, complicating interpretation.

• *检测方法与上述PGT-A相同。

PGT-SR（Preimplantation Genetic Testing for Structural Rearrangements）主要面向习惯性流产患者，检测特定染色体之间的结构异常，旨在预防胚胎移植后的流产。

被采集的卵子中，只有成熟卵子可以进行冷冻保存。此外，成熟卵子的受精率和妊娠率因采卵时的年龄而异。妊娠率是指在解冻后卵子存活且与精子受精，且受精卵质量良好的情况下的妊娠率。

Only mature eggs can be frozen from those collected. Even among mature eggs, the fertilization and pregnancy rates vary depending on the age at which the eggs were harvested. Pregnancy rates are calculated based on the survival of the thawed eggs and successful fertilization by sperm, along with the quality of the resulting embryos. The age indicated refers to the age at which the eggs were harvested.

● 冷冻卵子在解冻后的存活概率可参考以下报告

● The survival rate of thawed eggs has varied in reports.

● 1颗冷冻卵子在解冻后，卵子存活并成功受精（显微受精），且得到优良受精卵后的怀孕几率如下：

因此，考虑到卵子的存活率和随后的着床率，建议冷冻保存5个以上（最好10个以上）卵子。

● Pregnancy rates per egg after thawing frozen eggs, when the eggs survive, are fertilized (via intracytoplasmic sperm injection), and good-quality embryos are secured:

Therefore, considering the survival rate of the eggs and subsequent implantation rates, it is desirable to freeze and store at least 5 eggs (preferably more than 10).

卵子冷冻保存使用专用容器。每个容器最多可容纳3个卵子。冷冻保存的费用按容器计算。保存期限自采卵日起按年计合同。续期时需要提交续期申请书及费用。如果在续期预计月份过后未完成续期手续（同意书、费用），将被视为“无续期意愿”，并予以废弃。此外，建议每年续期时进行卵巢年龄激素（AMH）检查和超声检查，以评估未来怀孕的可能性。

Specialized containers are used for egg freezing and storage. Each container can hold a maximum of 3 eggs. Fees are charged per container for freezing and storage. The storage period is contracted on an annual basis from the date of egg retrieval. If you wish to extend the storage period, a renewal application form and fee will be required. If the renewal procedures (agreement form and fee) are not completed more than one year after the planned renewal month, it will be considered as “no intention to extend,” and the eggs will be discarded. Additionally, it is advisable to conduct ovarian age hormone (AMH) tests and ultrasound examinations at the time of annual renewal, if possible, to assess the potential for future pregnancies.